Sentence examples for repression of cellulase from inspiring English sources
These data suggest that creA is involved in repression of cellulase and xylanase production.
From our results, it is clearly evident that the expression and repression of cellulase and hemicellulase genes in A. terreus D34 varied with the type of growth carbon source.
Glucose inhibits cellobiose uptake [ 43] and could give rise to carbon catabolite repression of cellulase expression.
However, in solid state fermentation of A. niger, repression of cellulase activity by starch was not observed (Fig. 3).
Consequently, weakened BGL activity leads to decreased production of glucose via cellobiose hydrolysis, resulting in an indirect release from carbon catabolite repression of cellulase expression by glucose.
Furthermore, from the comparison between PC-3-7 and Cre1 disruptant of PC-3-7 it was assumed that Cre1 mutation gave rise to partial release from glucose repression of cellulase gene expression.
Whereas CRE1 is the main transcription factor mediating carbon catabolite repression (CCR) of cellulase gene expression, xylanase regulator 1 (XYR1) is absolutely necessary for activating the expression of most of cellulases/hemicellulases. Lack of XYR1 has been shown to eliminate cellulase induction by almost all inducers [ 4].
Growing the wild-type strain, QM6a, on glucose results in complete repression of the cellulase system.
The constitutive eno promoter driving the expression of Cel7A allows growth on glucose and results in repression of the native cellulase system, severely reducing background endo- and other cellulase activity and greatly simplifying purification of the recombinant protein.
Firstly, a mutation in cre1, a gene encoding a transcription factor mediating glucose repression for cellulase production was discovered.
Trying to find the key repressor of cellulase genes, we reasoned that such a regulator might be up-regulated under ER stress (mild as well as acute) and down-regulated under standard cellulolytic induction (Avicel only) compared to the repression condition on sucrose.
