Sentence examples for repression network from inspiring English sources

Our study identifies hnRNP I as an important player in this UCA1-mediated p27 repression network because the ability of UCA1 to repress p27 is dependent on the interaction of UCA1 with hnRNP I. Suppression of hnRNP I by RNAi decreases p27, as UCA1-siRNA does.

Our study identifies another important protein, hnRNP I, in this RoR-mediated p53 repression network because the ability of RoR to repress p53 is dependent on the interaction of RoR with hnRNP I and suppression of hnRNP I by RNAi substantially decreases the doxo-induced p53, as RoR does.

Fig. 4 Expression profiles of the hexose transporter genes and comparison of the transcriptional changes in the genes involved in glucose sensing and repression network.

These results are demonstrated with two existing biochemical networks, the Pentilator and a self-repression network of a Hes protein.

The removal of P or O from the system reduced the three-species network to a two-species cross-repression network similar to those that have been analyzed previously (Cherry and Adler, 2000; Saka and Smith, 2007) and resulted in N achieving its peak activation at lower values of G. Similarly, the removal of P and O resulted in N induction at even lower values of G.

For example, Cin5 has previously been implicated in Tup1-mediated repression through network analysis [33], and Tup1 and Yap6 were proposed to regulate a common set of genes based on analysis of expression in a tup1 mutant.

The net functional effect of miR-25 regulation of TGFβ signaling in NSPCs will depend on the relative expression, degree of miR-25 repression, and network connections of each member of the TGFβ pathway in NSPCs.

At the genomic level, repression of networks corresponding to major histocompatibility complex antigen presentation is observed in septic shock.

At the genomic level, repression of networks corresponding to major histocompatibility complex antigen presentation is observed in paediatric patients with septic shock [ 13].

The repression of the network of ECM-receptor interactions included numerous collagens, laminins, and integrin subunits (Fig EV2).

Importantly, the extensive Myc-mediated translation repression of the network of ECM and adhesion proteins was not compromised by Torin-1 treatment, showing that mTOR pathway is not involved in the regulation of this effect (Fig 4D).