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Repression causes untold misery by destroying opportunities for empathy, understanding and love, and instead fosters depression, substance abuse and anxiety disorders, with their enormous social and economic costs.
Ironically, once that threshold has been crossed, each act of regime repression causes the resistance to go up, which subsequently lowers the level of fear amongst the population.
In Drosophila, overexpression of autophagy‐related genes in neurons enhances longevity, while their repression causes neuronal defects and shortening of lifespan (Simonsen et al., 2008).
We demonstrated that 12-LO repression causes a defect in insulin - induced translocation of GLUT4 to the plasma membrane and 2-DOG uptake.
Forced expression of Imp-L2 results in induction of 4E-BP (a marker of insulin repression), causes non-autonomous growth inhibition and triggers many of the phenotypes associated with impaired insulin signaling, such as reduced fecundity, increased triglycerides and extended lifespan (Honegger et al., 2008; Alic et al., 2011).
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We hypothesized that these metabolic bottlenecks may be, at least in part, the effect of carbon catabolite repression caused by glucose or acetate, more preferred substrates that must be provided to the strain for supplementary energy and cell growth.
Set during the 1990 Mundial Soccer matches and just before the Gulf War, Mercedes is a film about Noubi, a gullible young idealist who lives in a world where cultural, political, economic, and sexual repression cause the world around him to seem strange and unrealistic.
Our results demonstrate that the ADH7 promoter can overcome the pronounced translation repression caused by the combined stress of vanillin, furfural, and HMF, and also suggest a new gene engineering strategy to breed robust and optimized yeasts for bioethanol production from a lignocellulosic biomass.
The Uprising and its repression caused trauma that continues to manifest in the Malagasy population.
This repression caused Ned's anger to build up inside him until he erupted at the townspeople.
Similar effects were obtained on Fibronectin RNA, another target of β-catenin [48], although in this case the repression caused by npPS1 was smaller (Figure 9B).
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