21, 78– 81 Given that both translational repression and mRNA decay are implicated in miRNA-mediated repression, one fundamental question arises: what are the relative contributions of these two mechanisms on repression?
Though he never exactly spells it out, the melancholy supposition arises that a repression of musical potential is the price we pay for our powers of ratiocination.
We also provide evidence to suggest that repression of crossing over at telomeres and centromeres arises from different mechanisms.
It is possible that this difference arises because the secondary pathway, Xist repression linked to the pluripotency program [ 18], plays a more dominant role in the ΔCpG XY ES cell line.
Ec.metJ itself shows fairly weak repression which is consistent with previous reports [ 10, 11] and arises from the fact that one of its three promoters is constitutive and non-repressible.
It is possible that negative contractile effects of obesogenic diets arise from repression of Akt and/or NOS signalling (Ren et al., 2010), whereas baseline Akt expression and NOS phospho-activation are enhanced in the current model.
An intriguing question arises from the hypothesis of cvhRNA regulatory networks is why virus evolves to facilitate rather than avoid miRNA binding which inevitably leads to repression of viral RNA function.
Similar hyperplasia arises when the Notch pathway terminal transcription factor Su(H) is expressed using the patched-Gal4 driver (ptc-Gal4; Figure 1B), despite its more restricted expression and its dual role in repression and activation of Notch targets.
There are others with similar stories in virtually every government department, including some of those now working as lawyers and judges for the Iraqi Special Tribunal, which is to try cases arising from the repression under Mr. Hussein.
When inspiring opponents of political repression, such as Andrei Sakharov and Fang Lizhi, have arisen from the ranks of scientists, it has been their personal courage, not their beliefs in the role of science in society, that has sustained them, and they were afforded no official backing from the scientific bodies of their countries.
