Sentence examples for repressing expression from inspiring English sources

In addition, MYC2 has been shown to be necessary for the jasmonate-mediated repression of root growth by directly repressing expression of PLT1 and PLT2[ 71].

It is plausible that the mutation in SMG11/D2 might decrease BR signaling or responses by repressing expression of BR signaling genes (e.g. OsBRI1 and BU1), resulting in small grains.

Consistent with this, the early pulse of SCL expression also expanded hematopoietic colony-forming cell numbers, while concomitantly repressing expression of paraxial and cardiac markers, and inhibited development of beating cardiomyocytes.

MicroRNA-133b is a small non-coding RNA which targets Sirt1s, suppressing its expression in hepatocellular carcinoma cells, increasing the proliferation and invasion of hepatocellular carcinoma cells through the activation of E-cadherin expression, and repressing expression of GPC3 and the anti-apoptotic proteins (Bcl-2, Bcl-xL, and Mcl-1) [26].

Using gain- and loss-of-function approaches together with a synthetic Zinc-finger polypeptide (6ZFP) engineered to prevent transcription factor binding to a defined cis element, we show that the transcription factor EBF1 promotes B cell lineage commitment by directly repressing expression of the T-cell-lineage-requisite Gata3 gene.

In amphioxus, AmphiHox1 has been shown to mediate the effects of RA signaling by repressing expression of pharyngeal markers in the posterior foregut/midgut endoderm [62].

Overall, our studies demonstrate that Hr evokes an anti-apoptotic response by repressing expression of p53 and pro-apoptotic events regulated by p53.

Expression data from analysis of the heme utilization mutants suggest the PrrH RNA is capable of repressing expression of at least one of these PrrF-regulated genes, m-acnA, under low iron conditions.

The transcriptional regulator Hmga2 is normally expressed in neural stem cells early in embryonic development, where it actively drives self-renewal by indirectly repressing expression of negative regulators of cell cycle progression [43].

Heme induction of acnB was impaired in the ΔphuR and ΔhemO mutants as well (Figure 7A); since heme is still capable of repressing expression of PrrH in the ΔhemO and ΔphuR mutants (Figures 3D and 6A, respectively), this data rules out a role for PrrH in repression of acnB expression.

TGFβ1 reduces autophagy, in part, by selectively repressing expression of autophagy mediators in normal lung fibroblasts.