Sentence examples for repressing activity from inspiring English sources

Since different cell types may have different levels of protein expression for each co-regulator, the overall balance of co-regulatory proteins with activating and repressing activity may determine whether tamoxifen has an estrogenic or anti-estrogenic effect.

Thus, in addition to its sleep-promoting role reported previously, SSS may also promote wake by repressing activity of nAChRs.

This indicates that linc-MD1, by binding miR-133 and miR-135, acts as a decoy abolishing miRNA repressing activity on both MAML1 and Mef2C 3′UTR.

On the other hand, small interference RNA (siRNA) was documented as playing pivotal roles in repressing activity of TEs in diverse organisms by specific targeting [ 44- 47].

Fourteen more nGRE elements were found also within the region, if considering one mismatch in the nGRE motifs with no spacer, one or two bp spacers (N = 0, 1 and 2), of which 10 had tolerable changes for repressing activity [ 26].

The redundant roles of WRKY18 and WRKY40 as repressors of plant defense genes are consistent with the demonstrated repressing activity of WRKY40 but not with the transcription-activating activity of WRKY18.

Thus, this immobilized template assay has the potential to study activating versus repressing activities concomitantly.

However, depending on the specific enhancer, GATA2 might have enhancing or repressing activities on gene expression, as was shown in the siRNA knockdown experiments.

As expected (Lee and Batzoglou, 2003), we found proteins with highly activated or repressed activity in an expression mode to usually have coherent biological roles (Supplementary Material).

This leads to the inability of Ebp1 to repress activity of E2F1-regulated cell cycle genes and inhibit cell growth.

Together, these results demonstrate the ability of NKX2-5 to repress activity from the Tnni2-Tnnt3-enh enhancer sequence.