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Together, our findings show that MES-4 and LIN-54 each have both activating and repressing capability, but act oppositely on common target gene sets.
It was observed that salinomycin significantly inhibited sphere forming-capability and repressed the expression of CD44 and BMI-1 by 3.2-fold and 6.2-fold, respectively.
Interestingly, we have shown that DC-SCRIPT also acts as a NR co-regulator having both repressing and activating capabilities [ 3].
In contrast to the H1.2 isoform, apoptogenic capabilities in the isoforms H1.1 and H1.3 are repressed by the kinase PKC with gene ablation and dominant-negative approaches identifying a role for the PKC- β1 isoform in this function.
Hxk2p is known to provide the main sugar-phosphorylating capability during growth on fermentable carbon source, and becomes repressed on non-fermentable carbon source by transcription factor Rgt1 (Palomino et al. 2005).
Capability of E. coli to co-utilise acetate simultaneously with glucose was strongly repressed with increasing dilution rates.
One potential interpretation is that in androgen-independent prostate tumors, the capability of transcription factors to initiate transcription and microRNAs to degradate mRNA are both repressed.
Repressed homosexual.
"Jimmy P". is thoroughly repressed.
TALK about repressed.
Even religion was repressed".
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