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The results are summarized in Table 4, and described in detail below. 1 (Blue) represents upregulated with respect to normal and -1 (Red) downregulated.
+ Represents upregulated.
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Negative ΔΔCt (relative quantification) values represent upregulated genes whereas positive values indicate downregulation of the markers.
The colour red was selected to represent upregulated genes and the colour green to represent downregulated genes.
The highly represented downregulated genes were CCNB1, CCND2, PTTG1, CXC12, and LGALS1, and the highly represented upregulated genes were ADM, MYC, NRG1, NRG2, and PPARG.
Transcripts with twofold greater abundance (2073 red dots) and two-fold lower abundance (4468 green dots) represent upregulated and downregulated transcripts, respectively, in response to PM infection.
In this integrated analysis the subset of proteins that were most successfully validated in human ovarian cancer sera represented proteins found to be upregulated in plasma from tumor bearing mice and found to be secreted in human ovarian cancer cells.
The luminal cells should be mostly represented by differentiated cells, and genes in these cells would be expected to be upregulated during HC11 differentiation.
They found that an unspliced lncRNA, which they designated " NKILA" (represented by large yellow box in Figure 1), could be upregulated by several immune agents.
Conversely, Spp1 has been reported to be upregulated in spinal hyperostosis of twy mice, which represent another Enpp1 allele (Aiba et al., 2009).
Red dots represent genes upregulated in C2C12.TAF7L-post C2C12.TAF7L-post represent genes unaltered or downregulated in cells.TAF7L-post cells compared to C2C12.CNTL-post cells after adipogenic induction.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com