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The nicotinic acetylcholine receptor (nAChR) represents the prototype of ligand-gated ion channels.
In this context, mixed cryoglobulinemia syndrome (MCs) represents the prototype of virus-related autoimmune-lymphoproliferative diseases.
Rheumatoid arthritis (RA) not only has a high prevalence but also represents the prototype of an autoimmune inflammatory joint disease that leads to progressive destruction of articular structures, particularly cartilage and bone [ 1].
SF2/ASF (Ge et al. 1991; Krainer et al. 1991), now designated Sfrs1 (Table I), represents the prototype of a family of splicing factors containing the RS domain, rich in arginine and serine dipeptides.
Following the discovery of hepatitis C virus (HCV) in 1989 as the major etiological agent of non-A-non-B chronic hepatitis [ 1], some epidemiological studies suggested its possible role in the pathogenesis of mixed cryoglobulinemia syndrome (MCs), which now represents the prototype of HCV-associated autoimmune-lymphoproliferative disorders [ 1- 4].
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Secondary-structure prediction and structure-based sequence alignment suggest that the GerBC structure represents the prototype for C subunits of nGRs from spores of all Bacillales and Clostridiales species and defines two highly conserved structural regions in this family of proteins.
The prothrombin RNA represents the prototype for the function of the USE (Danckwardt et al, 2007).
As such, managers represent the prototype of the white-collar salaried employee.
It was revealed that both carriers represent the prototype of previously unknown translocator families.
We propose that MCOH may represent the prototype of a new class of iron chelating agents to be developed for iron-removal therapy in vivo with the goal of preventing tissue damage caused by the iron redox cycle.
In Maud Ellman's words, 'eating comes to represent the prototype of all transactions with the other, and food the prototype of every object of exchange'.18 Restricted eating, then, can be experienced as empowering.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com