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𝒴 represents each HPO subontology in a vector space where component i represents term i.
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GO 0045786 (Negative regulation of cell cycle) is the most prominent disproportionately represented term.
Within these biological processes, the most significantly over represented term was oxidation-reduction process (GO 0055114, 92 genes within this term).
The same color dots represent terms which have similar biological functions.
In this figure, nodes with a check symbol represent terms included in the positive dataset.
Functional Group 15 represented terms linked with amino acid metabolism, suggesting an emphasis on protein synthesis.
The functional enrichment results are shown as a term relationship network, where nodes represent terms and edges show term relationships.
Document vectors were generated as weighted superpositions of 32,000-dimensional binary-valued elemental term vectors representing terms they contain.
Smaller P-values represent terms that are more likely to be erroneously reported as significantly enriched using the standard method.
For the biological process category, response to salt stress and cadmium ion were the most highly represented terms (Fig. 1).
In the BP category, the two most represented terms are "transcription" (1.82 % +/− 0.09 %) and "regulation of transcription" (1.81 % +/− 0.17 %).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com