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Vertical axis represents Reaction Time (RT) in millisecond (ms) while represents various stimulus size namely, Sti_10: Stimulus Size 10; StimulusSizeulus Size 20; StimulusSizeulus Size 30.
IOMA's QP problem is formulated as following: (6) (7) (8) where Equation (6) represents mass-balance constraint for the k-th flux distributions, Equation (7) represents reaction directionality and flux capacity constraints, and Equation (8) represents the estimated fluxes for the core reactions based on the proteomic and metabolomic data.
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Therefore, only the first H-migration from IN1-g-PA to IN2-g-PA via TS1-g-PA was considered to represent Reaction g.
As described in Methods, we represented reaction content of the models by EC numbers.
The functions R1,..., R19 represent reaction rates and are described in Table 5 along with nominal parameter values.
Reaction rules represent reactions at the reaction center only.
A significant difference is observed between the number of representing reactions for these templates in the respective networks.
Sets of probabilities representing reactions participating in ATRP or overall ATRP reaction probability were implemented in the simulation model.
Except for the templates in the 16 groups of Fig. 18, the majority has a very low number of representing reactions.
Resulting network was transformed into classical 1-mode view, where nodes representing metabolites are linked by edges representing reactions.
Each biochemical reaction in the metabolome of the organism is a node, and nodes representing reactions that share a common metabolite as a substrate in one reaction and a product in the other are connected by an edge.
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