Altogether, these values represented incremental cost effectiveness ratios of £555 for screening versus no screening, £10 013 for screening twice versus screening once, and £29 680 for lifetime rescreening versus screening twice.
This represents substantial incremental costs to an already costly condition, which has an estimated total annual cost of $10 billion (2010 US$ inflated from $6.8 billion 1994US$) [ 45].
Then we calculated the incremental cost-utility ratio (ICUR) across the experimental and control conditions, which represents the incremental costs (or savings) per QALY gained in the experimental condition relative to the control condition.
Next, we calculated the incremental cost-effectiveness ratio (ICER), which represents the incremental costs (or savings) per area of concern lost in the experimental condition relative to the control condition.
Then we calculated the incremental cost-effectiveness ratio (ICER) across the experimental and control condition, which represents the incremental costs (or savings) per 'success' (i.e. moderate to large improvement in depressive symptoms) in the experimental condition relative to the control condition.
Figure 3 graphically represents the incremental cost-effectiveness of assessed antipsychotics versus the primary comparator (haloperidol).
The steepness of the different line segments represents the incremental cost-effectiveness ratios.
Davis et al. found that all-cause healthcare claims in HCV infected patients were, on average, almost US$21,000 in the year after diagnosis, nearly four times that in age, gender, and plan-matched controls [ 20], while McCombs et al. found an average cost of over US$37,000 in the year following diagnosis, which represents an incremental cost of more than US$23,000 [ 22].
They are somewhat lower as they represent the incremental cost of a mandate for services partially already provided in baseline coverage, while the Virginia data represents total collected cost of lymphedema treatment.
