An NRS of unity represents perfect concordance between the NGS variant set and the array.
Plot represents the concordance rates between technical replicates and biological replicates (wgaDNA vs gDNA), where positions are only considered, when sequencing depth is greater than the Coverage (X-axis).
The c-statistic, calculated as the area under the Receiver Operating Characteristic (ROC) curve, represents the concordance between predicted probabilities and observed outcomes for all possible pairs of patients [ 20, 21].
The kappa statistic measures the extent of exact agreement, adjusting for chance agreement with values greater than 0.75 representing excellent concordance; values of 0.40 to 0.75 representing moderate concordance; and values less than 0.40 representing poor concordance [ 15].
10 Concordance for a staging system can range from 0 to 100 %, with 100%% representing absolute concordance, 50%% indicating no association (no better than flipping a coin), and 0%% perfect discordance.
The evaluations represent the concordance and the disagreement of class area distribution from the use of heuristic judgements and the objective datasets.
In the example, the PMI is therefore [50- -134 /90- -134 ], representing the concordance between the preference scores for the physician treatment recommendations and preference scores for the participants' preferred treatment.
These were subsequently merged in order to get voxel-wise and noise-corrected ALE-scores representing the concordance of results at a family-wise error (FWE) corrected p-threshold of p < 0.05 (Eickhoff et al., 2012).
jsDAS (http://code.google.com/p/jsdas/) is being used as a bridge between the framework and DAS servers; it automatically generates JavaScript objects representing, in concordance with the DAS 1.6 specification, the DAS responses.
Taken together, these data showed that (1) the two biological replicates represented excellent concordance with each other, which indicating the experiment was reliable and reproducible; (2) the morphological change of different root development stages could be well reflected by gene expression profiling.
