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Reverse cholesterol transport (RCT) pathway represents an important process involved in cholesterol homeostasis [1] [2].
The prediction of these mechanisms in COPD data sets showed that T-cell activation and migration in response to smoke-exposed lung represents an important process in the innate immune response.
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Decreased expression of DDR1 in MCs may represent an important process for mesangial proliferation.
C-terminal truncation may represent an important process for post-translational regulation of ADAMTS-5 activity in vivo and could potentially nullify the inhibition by antibodies directed against distal ancillary domains.
Hence, paracrine signalling by Caspase-3 or Caspase-7 may represent an important process in the maintenance of tissue homeostasis, by stimulating cell proliferation, migration and possibly differentiation, thereby replacing injured cells.
According to our observations, caspase-mediated cleavage of E-cadherins and the loss of cell-cell contacts are likely to represent an important process during the extrusion of apoptotic cells.
T. vaginalis cells are also known to form large cell aggregates (in a process called swarming or rosetting), which could represent an important process for pathogenesis [ 14], suggesting that specific cell-cell interactions also take place between cells of the parasite.
While non-cell autonomous control of tissue regeneration by Caspase-3 may represent an important process for maintaining tissue homeostasis, it may limit the efficiency of current cancer therapy by promoting cell proliferation in those cancer cells resistant to radio- or chemotherapy.
Transverse dispersion represents an important mixing process for transport of contaminants in groundwater and constitutes an essential prerequisite for geochemical and biodegradation reactions.
Gully erosion represents an important soil degradation process in rangelands.
Ca2+ mobilization from intracellular stores represents an important cell signalling process that is regulated, in mammalian cells, by inositol-1,4,5-trisphosphate (InsP3), cyclic ADP ribose and nicotinic acid adenine dinucleotide phosphate (NAADP).
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