Biases in amino acid substitutions might represent a substantial problem for phylogenetic analysis [ 53].
Thus, the results confirm suspicions that highly similar duplicate sequences represent a substantial problem when predicting tentative consensus transcripts from salmon ESTs.
iDILI represents a substantial clinical problem as it can arise from drugs that are very commonly prescribed and thus represents a widespread issue.
Cocaine use disorder is a very common condition that represents a substantial public health problem, and no effective pharmacological or psychological therapies have been identified to date.
It represents a substantial public health problem affecting 8 15% of women and can result in long-term adverse consequences for maternal mood and infant development[ 3].
Influenza and Influenza-like-illness (ILI) represents a substantial public health problem, but it is difficult to measure the overall burden as many cases do not access health care.
"This represents a significant problem.
Neonatal sepsis caused by E. coli represents a substantial worldwide public health problem.
Each operator represents a substantial investment by the plant owner.
