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Indeed, the traditional use of this family of highly nephrotoxic and carcinogenic herbs represents a significant problem for global public health.
Target site inaccessibility represents a significant problem for fluorescent in situ hybridisation (FISH) of 16S rRNA oligonucleotide probes.
It represents a significant problem for hepatobiliary surgery because of its high recurrence rate and the associated risk for partial hepatectomy.
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Patients who leave before being seen by a physician represent a significant problem for many emergency departments (EDs).
The lower lenses of all types of multifocal glasses blur distant objects in the lower visual field and this factor, in particular, may represent a significant problem for older people [ 3, 4].
Given the large number of potential pathogens including bacteria, atypical bacteria, and viruses, uncertainty regarding etiology represents a significant problem, particularly for patients ill enough to require admission to hospital.
"This represents a significant problem.
Driver distraction represents a significant problem in the public transport sector.
Lack of effective treatment of CRPC represents a significant problem in current management of PCa.
Severe hypoglycaemia still represents a significant problem in insulin-treated diabetes.
Water leakage is a significant problem for water companies.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com