Sentence examples for represents a significant obstacle from inspiring English sources

It represents a significant obstacle to intelligence analysts in their attempts to isolate indicators of future terror attacks.

The large degree of ALR redundancy coupled with an incomplete database of ALRs represents a significant obstacle in engineering E. coli for either aldehyde or alkane production.

We conduct a field experiment to show that discrimination in the rental market represents a significant obstacle for the residential mobility of immigrants and contributes to the ethnic residential segregation observed in large cities.

The fact that many biobanks or biobanking networks use different IT platforms and different message formats and terminologies represents a significant obstacle to communication with, within, and between biobanks.

Tumor hypoxia represents a significant obstacle in the management of locally advanced carcinoma of the uterine cervix, by increasing malignancy and inducing treatment resistance [ 5– 7, 12– 15].

Although packaging is essential and deletion of some chromatin-modifying factors is lethal, chromatin also represents a significant obstacle for DNA-binding factors to access their cognate sequences.

However, crowded NMR spectra represent a significant obstacle for the complete resolution of these anisotropic parameters.

However, in vivo delivery issues still represent a significant obstacle for widespread clinical applications.

Does climate/seasonality represent a significant obstacle for revegetation?

As the vemurafenib example shows, the rigid data requirements of the G-BA, together with the lack of methodological guidance, also represent a significant obstacle to obtaining a superior benefit rating in a re-assessment, even if new data are submitted.

Downregulaton of BRCA1 results in increased p53 and p21 expression [31], which may represent a significant obstacle to tumorigenesis that can be overcome by somatic mutation of the p53 gene.