Sentence examples for represents a significant issue from inspiring English sources

In this context, the spatial and the temporal rainfall variability represents a significant issue, especially for basins in which the rainfall field cannot be approximated through the use of a single station.

This represents a significant issue for effective individual and group situational awareness and would have impacted upon shared mental models of the situation, resources required, and decisions to be made (Section 3).

However, it is important to note that the role of other no-BCR-ABL abnormalities on the expression signatures of genes evaluated in this protocol represents a significant issue to explore, and therefore its effect on the prognosis value of these genes should be assessed.

In conclusion, this prospective observational study has demonstrated that alcohol-related admissions represent a significant issue to the ICU environment.

Drug interactions represent a significant issue in elderly patients on warfarin because of polymedication and frequent changes (adding or stopping) in concomitant medications related to intercurrent acute illnesses.

The burden of preterm birth and its complications have been increasing [ 2] and represent a significant issue in combating neonatal health risks and reducing neonatal mortality [ 3, 4], yet there is a paucity of research on care seeking for preterm newborns [ 5].

The safety of electroconvulsive therapy (ECT) in patients who have deep brain stimulation (DBS) implants represents a significant clinical issue.

We sequence many isolates of the malaria parasite P. falciparum as it represents a significant health issue in developing countries; this organism leads to several million deaths per annum.

Methamphetamine abuse has undergone a dramatic worldwide increase, and represents a significant and global issue for public health.

3 4 The obesity epidemic represents a significant public health issue, translating into an estimated annual cost of $21 billion in Australia, 5 further highlighting the need for physical activity and nutrition programmes capable of engaging this older group.

Back pain represents a significant public health issue, affecting approximately 70% of the population over the life course [ 1- 4], and incurring direct and indirect costs of greater than AU$8 billion per year in Australia [ 5- 7].