Sentence examples for represents a major obstacle from inspiring English sources

However, intrinsic and acquired TMZ-resistance represents a major obstacle for this therapy.

Thirst represents a major obstacle to the achievement of such a goal.

"This bias likely represents a major obstacle for women aspiring to prestigious careers in today's society," Bian writes.

Epigenetic silencing of transgene expression represents a major obstacle for the efficient genetic modification of multipotent and pluripotent stem cells.

The blood brain barrier (BBB) represents a major obstacle for the delivery and development of drugs curing brain pathologies.

The finding defies conventional wisdom about the sorts of foods consumers waste — and represents a major obstacle for environmentalists and anti-food-waste campaigns.

However, eventual resistance to these therapies is observed in the majority of cases, representing a major obstacle to long-term cures.

These are associated with parasite immune evasion and represent a major obstacle for subunit vaccine design.

Substantial and highly variable placebo response rates represent a major obstacle to antidepressant development in major depressive disorder (MDD).

However, data requirements, particularly for the more complex urban models, represent a major obstacle to their employment.

However, the artisanal processes of research and development are slow, expensive, and inconsistent, representing a major obstacle in biotechnology and bioengineering.