Sentence examples for represents a major difficulty from inspiring English sources

For this reason, the computation of dense gas flows still represents a major difficulty in ORC development, and there is a need for validation studies based on experimental data, which is currently hardly available.

Although gene ablation in T cells with DNA nucleofection of CRISPR reagents was also achieved, DNA nucleofection is associated with high toxicity to T cells, which represents a major difficulty for its application (Mandal et al., 2014; Su et al., 2016).

Vincent Delieuvin, the Louvre's curator of 16th century Italian painting, tells The Creators Project that, aside from the removal of the varnishes, the state of the painting represented a major difficulty, as it was unclear whether some areas were deteriorated, unfinished, or damaged due to earlier treatments.

The electronic platform Moodle was easy handling for the teaching staff, benefited from the IT back office of the University of Geneva, and did not represent a major difficulty for most of the students.

All told, the commitment by the Department of Parks and Recreation, which announced the timetable at a City Council hearing, represents a major leap forward for a three-year-old project that has been hobbled by technical difficulties and a lack of interest by major Internet providers.

Additionally, the actual identification of species as native or introduced and the difficulty in determining whether newly reported marine species are introduced or cryptogenic natives represents a major constraint.

The D.S.M. represents a major achievement.

It certainly represents a major increase.

A recession represents a major peril for a premium brand.

This represents a major fault line in the new arrangements.

More than mere tokenism, this language represents a major shift.