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We propose that spatiotemporal SERT expression in non-serotonin-producing neurons represents a determinant in early life genetic programming of cortical circuits.
The solutions of ∣B∣=0(where ∣·∣ represents a determinant) give the natural frequencies of the "constrained" beam and the substitution of each corresponding values ofCj j=1∽4) into the eigenfunction will define the associated mode shapes.
Figure 3A shows that GE binds to the genetically-defined GE target, confirming the hypothesis that the GE target represents a determinant for binding of GE to RNAP.
In endothelial cells, it has been described that TGFβ/ALK5/Smad2/3 signaling antagonizes TGFβ/ALK1/Smad1, and that the balance of TGFβ/ALK1 versus TGFβ/ALK5 represents a determinant of the pro- and anti-angiogenic effects of TGFβ [7].
Abe et al therefore propose that the N-terminal extension of the β subunit represents a determinant of the E2P stabilisation of H+,K+-ATPase, preventing the reverse reaction from occurring and thereby keeping the gastric epithelial membrane resistant to the steep pH gradient.
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In addition, hippocampal atrophy may represent a determinant of neuropsychological sequelae [25], including depression, anxiety, and posttraumatic stress syndrome [91].
In early breast cancer, local relapses represent a determinant and not simply an indicator of risk for distant relapse and death.
The result further suggests that a high Kow is probably not associated with increased ACRs and does not necessarily represent a determinant for chronic toxicity testing within this context.
These observations together with in vitro data [17] suggest that chromatin structure may represent a determinant factor for target-site selection during retroviral integration.
To investigate whether Cys redox potential could represent a determinant of pro-inflammatory cytokine levels in humans, we examined IL-1β, TNF-α, Cys, and CySS in plasma samples from 16 healthy adults.
A statistically significant difference (p<0.001) was observed in terms of number of adverse outcomes in the follow-up, suggesting that the low serum levels of TRAIL measured at discharge after AMI represent a determinant of mortality and HF at 12 months of follow-up in this study population.
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