Table 4 displays the estimated terms for the basic demographic parameters of the IM model using NRY and mtDNA datasets from Southwest Angola and Southeast Africa, assumed to represent the endpoints of the western and eastern branches of the Bantu migrations, respectively (see Additional file 6).
J. Reid Meloy, a forensic psychologist and expert on mass killers, has noted that almost without exception, their crimes represent the endpoint of a long and troubled highway that in hindsight was dotted with signs missed or misinterpreted.
Our data profile DNA methylation patterns in adult tissue, and may represent the endpoint of the developmental methylation trajectory of cerebral and cerebellar cortices.
The growth of metastases represents the endpoint of many lethal events that few tumor cells can survive.
The metabolome represents the endpoint of the omics cascade and is also the closest point in the cascade to the phenotype.
Even if under perfect circumstances specific molecular signals can be detected and localized reliably, this information represents the endpoint of investigation because the cells cannot be studied further with respect to their function.
Spinal cord atrophy represents the endpoint of neurodegeneration resulting from an accumulation of multiple pathophysiological events, such as axonal degeneration and demyelination, axonal dieback and neuronal loss (Dusart and Schwab, 1994).
Taken together, a series of studies over the last decade has shown that the tyrosine phosphorylation and signalling potential of docking proteins such as those of Gab, IRS, FRS and SLP families is counteracted by their Ser/Thr-phosphorylation, which usually represents the endpoint of feedback loops from cytoplasmic signalling cascades [ 13, 15, 49, 81, 169, 177, 181].
Note: ↓ indicates that alternative assumption would likely reduce the net benefit estimate; ↑ indicates that alternative assumption would likely increase the net benefit estimate First, if the environmental externalities represent the endpoint of our analysis, it is clear that resolving uncertainties related to mortality will be more important than resolving uncertainties related to morbidity.
