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The homogeneous agreement model thus has two components: the first representing chance, the second representing agreement.
Kappa can range from -1 to 1, with 0 representing agreement no greater than chance.
Negative ICC values reveal greater within-subject variability than between-subject variability, representing agreement that is even less than expected by chance alone.
This approach provided for every dataset two gene lists with the intersect representing agreement and the symmetric difference representing different biological interpretations, which are solely caused by the different noise models (cf. Table 2, columns 'Comm. genes' and 'Diff. genes').
Agreement of the individual studies raw microarray data was estimated by the Integrated Correlation Coefficient Analysis, which produces the general Integrated Correlation Coefficient (ICC), representing agreement between studies, and can be interpreted in the same way as Pearson correlation coefficient.
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SMPTE 274M represents agreement on colorimetry according to the international standard Rec.
The kappa measure lies on a scale from −1 to 1, where negative values represent agreement less than chance, 0 represents agreement no more than chance, and 1 represents perfect agreement [19].
Note that, both matrices are triangular since they represent agreement and there is no true and predicted value.
The radial axis joining 0 to 180° is a 45° clockwise rotation of the line of identity in the four-quadrant plots, and represents agreement.
GT only represented agreement among three IRs using all available data.
Kappa coefficients represent agreement corrected for chance overlap due to category prevalence.
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