Sentence examples similar to representing a substantial difficulty from inspiring English sources

The time points of all participant-related actions to be taken during the study period are presented in table 1. Retaining participants in a clinical trial of long-term duration represents a substantial difficulty for research teams.

Intermediate cases therefore represent a significant difficulty.

The item "difficulty climbing stairs" could seem to be important because climbing stairs represents a substantial effort, and was also identified by patients as a priority during interviews and focus groups [ 11].

In the case of the SBT fishery this difficulty was compounded by the fact that the introduction of ITQs was accompanied by a TAC that represented a substantial reduction in the annual catch taken in the proceeding few years.

This would represent a substantial benefit.

Each operator represents a substantial investment by the plant owner.

Yet "smoking very clearly represents a substantial health risk".

This represents a substantial potential savings in energy.

"This represents a substantial proportion of G.S.K.'s outstanding litigation.

Evaluation represents a substantial component of the concept of Disease Management Programmes.

A spokeswoman for AT&T Broadband, Sarah Eder, said services that Excite@Home provides represent a "substantial contribution".