Your English writing platform
Discover LudwigExact(13)
The three represented terms have been empirically observed as intrinsic within self-sustaining living systems, both in ecosystems and socio-economic systems.
Functional Group 15 represented terms linked with amino acid metabolism, suggesting an emphasis on protein synthesis.
For the biological process category, response to salt stress and cadmium ion were the most highly represented terms (Fig. 1).
In the BP category, the two most represented terms are "transcription" (1.82 % +/− 0.09 %) and "regulation of transcription" (1.81 % +/− 0.17 %).
In the molecular function ontology class, the most represented terms describe catalytic (33.3%) and hydrolase activity (20.0%).
In the more restricted set of heavily represented terms there is an apparent an over-representation of genes related to transcriptional regulation, nucleotide binding, and metal ion binding.
Similar(47)
Downregulated genes belong to nine enriched over-represented terms representatively including GO 0003723 (RNA-binding), GO 0008026 (ATP-dependent helicase activity), GO 0006397 (mRNA processing), GO 0006334 (nucleosome assembly) and 4 under-represented terms GO 0019538 (protein metabolic process), GO 0004175 (endopeptidase activity).
We defined the quality measure GO50, representing the percentage of highly over-represented terms for which the negative logarithm of the p-value drops at most by 50percentt (e.g. from p = 10-12 to p = 10-6).
As the Bonferroni method can be unnecessarily over-conservative, we report over-represented terms that are significant before Bonferroni correction as well.
Statistically over-represented terms were then mapped to the GO directed acyclic graph.
Many under-represented terms were related to inter-cellular communication (cell communication, receptor activity, signal transduction).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com