(2) A Problem score 0-7 is obtained by summing each of the seven items after they had been dichotomized, such that ratings of 1 or 2 represented "no problem", and ratings of 3, 4 or 5 represented "problem present".
3. Do you forget where objects were left? 4. Do you have difficulties to find the appropriate words? 5. Do you have difficulties in managing daily activities, which earlier represented no problem?
Four questions covered memory impairment (Have your memory deteriorated?), visuo-spatial skills (Do you forget where objects were left?), speech difficulties (Do you have difficulties to find the appropriate words?) and activities of daily living (Do you have difficulties in managing daily activities, which earlier represented no problem?).
Each is scored on a three-point scale representing no problem, some problem and extreme problem.
A 1-to-3 scale is used for each dimension, representing no problem, some problem, or extreme problem for the subject to engage in the activity alone; for the pain and anxiety items, the three ratings relate to the severity of symptoms.
The responses to the two sexual enjoyment and arousal questions and the burden of kidney disease on sex life question were recorded on a five point Likert scale, ranging from 1 to 5 (1 representing no problem or not bothered and 5 indicating a severe problem or extremely bothered).
The scores are transformed using a 0 100 scale, with zero representing extreme problems and 100 representing no problems.
MSIS-29 scores can be categorized so that 0 19 represent "no problems"; 20 39, "few problems"; 40 59, "moderate problems"; 60 79, "quite a few problems"; and 80 100, "extreme problems" [ 20].
It classifies health states on five dimensions (mobility; self-care; usual activities; pain/discomfort and anxiety/depression) with three severity levels each: level one represents no problems; level two represents some problems; and level three represents extreme problems.
Anxiety/depression and health status were measured with the EQ-5D, a generic measure of health status with three levels representing no problems, some problems, and extreme problems.
Each dimension has three possible levels (i.e., 1, 2, or 3), representing "no problems", "some problems", and "extreme problems", respectively.
