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In all the samples, that represented cells transfected with mutants, the wound gap was much smaller than that seen in the sample that represented cells transfected with c-CBL WT (p<0.001).
These colonies represented cells in which the α-toxin gene, plc, had been disrupted by the Targetron.
It has been shown that DMs separate into single minutes during G1-phase [15] and it could therefore not be excluded that outlier cells with higher copy-numbers than a specific colony's modal value represented cells where the DMs had just separated into single-minutes, leading to a duplication of the actual DM copy-numbers.
Although we also noted GFP-positive cells inside the EB at day 9, these internal GFP-positive cells did not express Afp mRNA (compare Figure 11P to Figure 11Q) and likely represented cells that had downregulated Afp expression but remained GFP-positive due to perdurance of the GFP protein.
Also, keratinocytes, which are the most represented cells in the epidermis (90%), can internalize penetrated materials.
However, in the GSC DNA histogram, the first peak represented cells at G1/late G2/M phase, and the second peak represented cells at S phase and early G2 phase (Fig. 6A– E).
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Among these 48 genes, two major pathways are represented; cell cycle and stroma-associated.
The first peaks, above channel 200 represent cells in G1, the second peak represents cells in G2 phase of the cell cycle.
Lane 1 represents cells treated with G-Rh2 alone, lane 2 represents cells co-treated with G-Rh2 and caspase-9 inhibitor, and lane 3 represents cells co-treated with G-Rh2 and caspase-8 inhibitor.
The first and second rows represent cells and contexts assigned to cells.
Nodes in the network represent cells that are able to create, consume and forward hormones.
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