Dyslexia represents a difficulty with reading, she says, not with thinking skills, one that "does not reflect an overall defect in language," but rather a weakness in a part of the language system.
To find the slope at a desired point, the choice of the second point needed to calculate the ratio represents a difficulty because, in general, the ratio will represent only an average slope between the points, rather than the actual slope at either point (see figure).
In sum, problems in employment represent a difficulty both because of reduction in efficiency and restriction in time.
This represents a difficulty with 1dPCH.
Also the issue of choosing the number q of different discretized states represents a difficulty.
The lack of a non-critical illness control or comparator population also represents a difficulty.
While the need for better diagnostics and treatments are clear, the complexity of the pathogenesis of the disease represents a difficulty in achieving those goals.
Parametrial lymph nodes are often involved by tumour cells and represent a difficulty in detection by a handheld gamma probe due to the 'shine through' effect of the primary tumour.
Vincent Delieuvin, the Louvre's curator of 16th century Italian painting, tells The Creators Project that, aside from the removal of the varnishes, the state of the painting represented a major difficulty, as it was unclear whether some areas were deteriorated, unfinished, or damaged due to earlier treatments.
The complexity of hardware design methodologies represents a significant difficulty for non-hardware focused scientists working on accelerating the simulation of complex bio-inspired applications.
For this reason, the computation of dense gas flows still represents a major difficulty in ORC development, and there is a need for validation studies based on experimental data, which is currently hardly available.
