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Representative structures were selected for each structural cluster with Tanimoto coefficient (Tc) less than 0.9 to other clusters.
Figure 3 shows the structural fold and topology diagram for representative structures belonging to PTL, eIF4-E, and BLES03 families.
We propose that discriminant clusters identify the representative structures in each class, and common clusters represent the similarities between classes.
The computationally generated conformations were structurally clustered on the basis of RMSD resulting in ten representative structures.
Structural genomics initiatives have attempted to remedy these deficiencies by systematically solving representative structures of major fold classes.
g, Representative structures for the two states highlighted in d.
New advisory arrangements have been created and existing representative structures have been defunded.
As representative structures we chose hexapeptides 1 8.
It should be noted that these representative structures fall within a rather shallow basin in the energy landscape.
The structures were clustered into 7 representative structures for model 1, and 5 for model 2 (Fig. 1, step 4).
Representative structures for each ligand were analyzed and binding modes were selected according to the mutagenesis data.
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