By being a real, representative, non-Hallmark American, Markle, whose fiancé is fifth in line for the throne — and whose grandfather-in-law will be the racially unnerving Prince Philip — is helping expand the royal fantasy and the royal reality, too.
By being a real, representative, non-Hallmark American, Markle, whose fiancé is fifth in line for the throne and whose grandfather-in-law will be the racially unnerving Prince Philip is helping expand the royal fantasy and the royal reality, too.
Next, we investigated the level of phosphorylated tau (p-tau), another representative pathological hallmark of AD.
In this work, through proteomic profiling of the G1 stage of MCF-7 cells, and by making use of publically available information and bioinformatics tools, we uncovered a highly interconnected network of nuclear and cytoplasmic cancer markers with regulatory role in biological processes representative of all hallmarks of cancer.
We illustrate the methodology by calculating outcomes for adjuvant treatment of gastrointestinal stromal tumours with imatinib mesylate, which selectively inhibits the activity of a cancer-causing enzyme and is a hallmark representative for the new generation of cancer drugs.
Imatinib mesylate reduces GIST cell proliferation by binding to the catalytic pocket of the KIT protein product (Schindler et al, 2000), and serves as a hallmark representative for the emerging generation of cancer drugs that selectively inhibits the activity of cancer causing genes or their protein products.
The strength of our biomarker collective is that we did not focus on a single process, but chose and combined markers representative of main cancer hallmarks (Hanahan and Weinberg, 2000) in colon cancer.
"Today's budget bears all the hallmarks of the Bush legacy," Representative John Spratt, the South Carolina Democrat who heads the House Budget Committee, told The A.P. Some Republicans were also critical.
One of the hallmarks of the DU145 cell line, a representative of androgen depletion-independent cancers, is the loss of androgen receptor.
To make them too interesting, I suppose, would make them less representative of the self-delusion and listlessness that are, apparently, hallmarks of the modern condition.
