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It takes a writer of significant qualities to avoid such a story becoming schematic, its characters reduced to representations of positions and outcomes.
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Cartesian representations of position, velocity, and force are gradually introduced to provide the player with tools to exert greater levels of control and prediction over what unfolds in the world space.
Hence, it is with some confidence that we can say that the hippocampal voxels that survived the rigorously controlled thresholding that we employed were associated with internal representations of position within the environment alone.
Our sampling evolved as analysis progressed, ensuring that we had enough representation of positions and roles to give us confidence in our findings.
Open image in new window Fig. 1 Vector representation of position updating using STPSO.
It has recently been suggested that coupling between modules or via feedback loops to the hippocampus may help to suppress noise and underpin a robust code (with a large capacity) for the representation of position [45].
The likely (posterior mean) path for a basic representation of position over time.
We examined the statistical over-representation of position-specific C-terminal tripeptides in 7 eukaryotic proteomes.
ZifBASE will be developed further to include graphical representation of position of ZF motif based on a score function and prediction of ZFP DNA-binding site from the given amino acid sequence.
This knowledge could, in principle, be informed by path integration, the self-motion-tracking process that updates the internal representation of position independently of landmarks (Mittlestadt and Mittlestadt, 1982; Etienne and Jeffery 2004; McNaughton et al., 2006).
The Clover program, run via the MotifViz web interface [ 59], was used to search for over-representation of position weighted matrices (PWMs) for octamer [ 93], Oct4 [ 60], Oct-Sox [ 60], KLF4 [ 54], E-box, GATA-1 [ 94] and CACC (KLF-A) elements in these promoter sets.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com