Sentence examples for representation of mutations from inspiring English sources
Here, we show striking intratumoral clonal diversity within FL tumors in the representation of mutations in the majority of genes as revealed by whole exome sequencing of subpopulations.
Another difference is the representation of mutations.
Open image in new window Figure 4 Graphical representation of mutation operator.
Nevertheless, given the similaritities in the frequency of D-loop variants observed in the current study and those observed in previous studies, albeit on individuals with HCC from different disease aetiologies (Nishikawa et al, 2001; Kubo et al, 2003), indicate that these data give an accurate representation of mutation frequency within the sequence of mtDNA analysed.
There the authors described a number of pathways affected by aging and also concluded that genes for which down-regulation was evident had an over-representation of mutation in gene promoters.
Also, despite the increased representation of complex mutations, many CNS metastases nonetheless occurred in cancers containing hotspot (substitution) mutations in TP53, reducing the likely sensitivity of detection of complex mutations as predictors of future CNS metastasis.
Thus, we determined the quantitative changes in the fractional representation of HA mutations during the course of infection.
As we studied a large number of unselected cases with good representation of index mutations, the results are robust and directly relevant to current management of mCRC.
Search results include a graphical representation of the mutations and a table that can be downloaded in tab-delimited format and further analyzed by Microsoft Excel or simple scripts.
This distribution of KRAS mutational subtypes in the pancreatic cancer cell line panel mimics the frequency of these subtypes seen in tumours from pancreatic cancer patients (Smit et al, 1988; Grunewald et al, 1989; Nagata et al, 1990), indicating that this panel is an appropriate representation of KRAS mutations in the human disease.
Currently, rs80357713 is associated with 12 different annotations on dbSNP, none of which is the standard clinical representation of the mutation: BRCA1 c.68_69delAG [ 2, 3].
