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Furthermore, the used graph representation of connected voxels can be used to examine the organization of the functionally connected resting-state brain [19], [43] and possible disruptions in network organization in patients [39].
Open image in new window Fig. 2 A representation of connected vehicles and infrastructure (courtesy of [16]).
This depth information can be conveyed either indirectly via two or more views of the scene (e.g. left and right views) or explicitly through either depth maps of geometric representation of connected 3D points and surfaces.
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Additionally, we found strong representation of terms connected to enzymatic activity.
(A ) Brain wide representation of regions connected to the thalamic seed during the awake and unconscious states (n = 16).
(G ) Brain wide representation of regions connected to the thalamic seed during the recovery state (n = 15) displayed on the MNI152 standard volume.
However, the small size of the dataset compels us to use the binary representation of these connections (connected or unconnected).
To avoid spurious over-representation of highly connected ('hub') proteins in reconstructed pathways (as they connect most protein pairs in the network in the most efficient way), we determined the confidence in each edge (P-value) according to the degree of the adjacent nodes in the observed network, such that edges that involve highly connected proteins are penalized.
Although correlation between adjacency and connectivity may account for the over-representation of reciprocally connected doublets, why such correlation would exist in C. elegans remains unclear.
The over-representation of reciprocally connected doublets in C. elegans has been explained [ 6] as a consequence of correlation between adjacency and connectivity of neurons.
Next, we discuss whether C. elegans can provide a clue to the functional significance of the over-representation of reciprocally connected doublets.
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