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For anodal stimulation, the active electrode was placed over the hand representation field of the motor cortex and the reference was placed above the contralateral eyebrow according to the international 10 20 system for EEG electrode placement.
4) Stem cell mediated functional improvement was achieved exclusively through recovery of the original representation field.
This return of activation in the original representation field was accompanied by an ongoing behavioral improvement pattern.
Therefore, these latter 2 implanted animals had no chance to recover function, since the original representation field of the forepaw was destroyed by the ischemic lesion.
Furthermore, the present finding is extending the earlier report that already spontaneous recovery in this stroke model is exclusively taking place by reactivating the original representation field in the S1 cortex [10].
Activation was always observed at the original representation field of the forepaw in the sensorimotor cortex (S1FL), and no signs of plastic reorganization were observed on those brains (Fig. 4, lower rows).
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To address these two questions, we have decided to investigate stem cell mediated functional improvement by use of a non-invasive imaging technique, in particular functional Magnetic Resonance Imaging (fMRI), which allows to detect, localize and characterize activated cortical representation fields to a specific sensorimotor stimulus.
With increasing body size the increased muscle mass and increase of peripheral receptors also lead to an increase of the corresponding central representation fields in the cerebral cortex (motor cortex, somato-sensory cortex).
In this work, the accuracy of a VRP representation of field work is confirmed and the ability of this optimization system to reduce field work times is verified.
Figure 5 Schematic representation of field experiment.
It is known also as the second quantization representation or field representation.
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