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We focus largely on biased technology platforms that are capable of analyzing a large panel of known analytes, as opposed to techniques such as two-dimensional gel electrophoresis (2DIGE) or mass spectroscopy that represent unbiased approaches (as reviewed in 1).
Although the sampling fraction is relatively small, the weighted numbers calculated by the method suggested by the CDC represent unbiased national estimates of the US ambulatory medical care population.
The mean values of the bootstrapped estimates represent unbiased estimations of the parameters under investigation.
Therefore, the distributions of mutations obtained in our study represent unbiased snapshots of genome-wide mutagen-induced base substitutions.
Genomic approaches represent unbiased and powerful tools to uncover the molecular basis of these complex mechanisms and they may also contribute to discover new biomarkers for these diseases.
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(No reduction represented unbiased scoring).
This work represents unbiased, independent research funded by public agencies from Portugal and Norway.
The parameter C, defined as the mean of the z-standardized hit and false alarm rates, served to represent response bias (ranging from −1 to 1, with 0 representing unbiased response behavior).
If we were to estimate the "true" effects of each of the two pollutants on daily mortality, then β1 (in Equation 1) would represent the unbiased effect of SO2, and β2 the unbiased effect of PM10.
Using the notation (hat {x}) to represent an unbiased estimate of x, it follows from [17] that begin{array}rcl@ mathbb{E}_{boldsymbol{r}} left[(boldsymbol{theta} - boldsymbol{hat{theta}})(boldsymbol{theta} - boldsymbol{hat{theta}})^{H}right] geq boldsymbol{J}^{-1}(boldsymbol{theta}), end{array} (5).
On the other hand, although use of RNA mapping on whole-genome tiling arrays seems to represent an unbiased approach [18], this method often yields many false-positive and false-negative values.
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