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Of note, these values were mostly determined shortly before the next transfusion and therefore represent trough levels rather than average concentrations during HIP treatment.
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Model residuals represent all the unpredictable variation in vancomycin trough levels.
Although study endpoint for the olanzapine LAI study was at 8 weeks (vs. 6 weeks for the oral studies), endpoint results represent the best comparison as these indicate trough levels for each of the formulations and dosage regimens, including the 4-week LAI dosage which would otherwise not be at trough level at 6 weeks.
CNI trough levels may be high or normal, and pain was correlated to elevated trough levels in some studies [ 8, 14] but not in others [ 10, 25].
One patient had insufficient trough levels for the first time.
At trough levels, the antibiotics achieved kill rates from 61%to97.6%61%to97.6%
The trough levels were measured.
FVIII trough levels were measured daily.
** High serum trough levels are defined as >5.0 mg/L.
Notably, low trough levels were associated with a high GFR.
There are many reasons for changes in tacrolimus trough levels.
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