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This is highly relevant, since they represent targets for future promising clinical investigations.
Little is known, however, about the pathways involved in the oncogenic effects of SMARCB1 inactivation, which might also represent targets for treatment.
These novel pathways represent targets for future metabolic engineering, as they would exploit both the rapid Entner Doudoroff glycolysis, and the energetically uncoupled electron transport of Z. mobilis.
Assemblies of organic molecules that form finite structures represent targets for crystal engineers that can exhibit properties largely independent of crystal packing.
We furthermore analyze how such signaling modules represent targets for the design of novel intervention strategies using established compounds and powerful combination therapies.
In line with the current interest in protein kinases inhibitors as potential drugs against a variety of diseases, the possibility that protein kinases may represent targets for novel anti-parasitic agents is being explored.
The cellular and molecular mechanisms implicated in age-associated changes in myocardial structure are of paramount importance since they cause profound alterations in the functional response and represent targets for alleviating age-related pathologies.
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Specific biomarkers indicating immune quiescence and representing targets for novel tolerance induction protocols are needed.
More coalition soldiers unfortunately represent more targets for the enemy.
Cardiovascular and metabolic risk factors represent potential targets for intervention.
These adherence proteins represent possible targets for the development of novel antimalarial drugs.
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