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NIL, ASCUS, and LSIL samples were used to represent specificity and HSIL and Cancer samples were used to determine sensitivity.
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Horizontal axis and vertical axis representing specificity and sensitivity respectively.
Our results indicate that RD4 deletion is not specific to any PFGE group or subgroup, and that it does not represent a specificity of recent French or Finnish isolates.
Therapeutic index is a widely employed parameter to represent the specificity of antimicrobial reagents.
Five distinct groups (I-V) are observed which represent different specificity clusters.
At present, the largest databases which are generally available, such as TRANSFAC [6] and JASPAR [7], represent binding specificity using an ungapped position weight matrix (PWM) representation.
Thus, we defined 50% sequence identity as a cut-off value to represent similar specificity.
To represent the specificity of SH2 domains in this study we define position weighted matrices (PWMs) based on the array-positive peptides.
Position frequency matrices (PFMs), the most widely used models to represent binding specificities, are experimentally characterized only for a small fraction of all TFs.
In order to confirm if two different S-RNase sequences represent different specificities, ideally crosses should be made between individuals harboring these sequences.
Previous data suggest that recombinant uricase does not competitively inhibit binding of anti-pegloticase Ab to pegloticase [ 13], indicating that anti-uricase and anti-pegloticase Ab represent separate specificities of Ab binding.
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