Exact(1)
Both the 1q12 expansion and the 1p11.2 q21.2 inversion represent major alterations in the genome architecture of the pericentric region of human chromosome 1, and as such, may have played key roles in the rapid HLS DUF1220 triplet expansion.
Similar(59)
Post-visit, there will unlikely be major alterations in India's behaviour.
Such events represent major replication errors, involving substantial alteration of protein 3° structure and causing regions of exact repeating 1° structure, both of which are generally considered deleterious to protein folding.
These represent major insights, not minor ones.
Individually these represent major public health priorities.
The organization representing major drugstores opposed it.
The World Umpires Association still represents major league umpires.
Such mutations represent one of the major alterations that might explain the different histological types found in ovarian cancers.
(2 Powerplant major alterations.
(4 Appliance major alterations.
maintains that both major parties need major alterations.
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