Sentence examples for represent hallmarks from inspiring English sources

Impaired insulin secretion from pancreatic β-cells together with insulin resistance in peripheral tissues represent hallmarks of type 2 diabetes (T2D).

These changes represent hallmarks of EMT.

Dysfunction and loss of insulin-producing pancreatic β cells represent hallmarks of diabetes mellitus.

Alternatively, these reductions in capacity for protein synthesis and chaperoning may represent hallmarks of temperature compensation at the cellular level in these fish.

The fitness effects of SP in males and females appear to represent hallmarks of interlocus sexual conflict (Rice 1998; Chapman et al. 2003a; Arnqvist and Rowe 2005), in that repeated receipt of SP exacerbates the survival cost of mating in females (Wigby and Chapman 2005), while simultaneously increasing a male's "per mating" offspring production (Fricke et al. 2009).

Because systemic endothelial dysfunction and shallow placental implantation/spiral artery remodeling represent hallmark abnormalities of preeclampsia [ 11], ENG's potential role has been investigated.

The changes in Bcl-2 and Bax expression were accompanied by cleavage of procaspase-3 and PARP-1 that represent hallmark features of cells undergoing apoptotic cell death.

Vγ9δ2 and Vδ1 expression, rapid response to phosphoantigen ligands, as well as BCG-induced activation so far represented hallmarks of γδT lymphocyte-mediated cytotoxicity towards phosphoantigen-expressing mycobacteria [58].

Furthermore, they clarify that deranged glucose stimulated insulin secretion (GSIS) and over-nutrition-induced apoptotic/necrotic β-cell death are the result of mitochondrial dysfunction, representing hallmarks of T2DM.

These niches represent the hallmarks of malignant gliomas (vascular proliferations, hypoxia/necrosis) and bear analogy to the microenvironments in which physiological stem cells in the brain are found.

Common alterations of the signal transducing network seem to represent molecular hallmarks of cutaneous melanomas and therefore should continue to strongly stimulate design and testing of targeted molecular interventions.