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These demographic shifts represent enormous challenges for governments at all levels.
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The establishment of a sustainable vegetation layer on shotcrete walls subjected to road environment represents enormous challenges.
However, care for these individuals represents enormous challenges for the health care services [ 22].
Both will be enormous challenges to Brazil's organizational abilities.
The systems themselves represent enormous diversity.
The also represent enormous, yet unfulfilled promise.
Most genital microbial pathogens represent an enormous challenge for developing vaccines that can induce genital immunity that will prevent their transmission.
MDR bacteria represent an enormous challenge to modern health care systems.
These concerns represent an enormous challenge for the research community and regulatory and ethics oversight agencies locally and internationally.
These and countless similar questions represent the enormous challenge still facing researchers as they strive to make personalized medicine a clinical reality.
Given the urgency of research and development in the face of the devastating HIV pandemic, these ethical concerns represent an enormous challenge for investigators, sponsors and Research Ethics Committees (RECs) both locally and internationally.
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