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Data points with a detection p-value>0.05 are masked as "NA", and represent beta values with non-significant detection of DNA methylation compared to background.
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The x-axis represents various gene features in protein coding genes (TSS1500 - 1,500 bp upstream of transcription start site, TSS200 - 200 bp upstream of transcription start site, 5′ UTR – 5′ untranslated region, 1st exon, gene body and 3′ UTR – 3′ untranslated region) and the y-axis represents beta value which is an estimate of methylation level.
This value is strong enough to represent beta diversity and the division into two plant communities is accepted.
Each dot represents a miRNA and the x-axes represent estimated beta values for the Oslo2 cohort from the univariate analysis.
The y-axes represent estimated beta values for the DBCG and TCGA data sets, respectively, from the univariate analysis.
(A) Promoter methylation level and corresponding transcript abundance Methylation levels are represented by Beta values and transcript abundance is represented by FPKM values.
The thickness of the edges represents relative beta values.
The normalized data, presented as beta values, represent the degree of methylation at each CpG site, with 0 being unmethylated, and 1 being methylated.
Explicitly modeling the duration of each event ensured that the resultant beta values represented an estimate of the neural response per unit time spent solving the problem.
These regression analyses were conducted separately for each participant, and the resulting six beta values, representing each pairwise comparison of two contrasts, were entered into one-sample t-tests to test for significant results across participants.
Previous studies have shown that probes with beta values <0.3 represent unmethylated areas of the genome [ 20] and we therefore defined unmethylated probes on this basis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com