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Silencing by microRNAs has been proposed as a mechanism to avoid unregulated expression of R genes which may be a threat to the plant and represent a fitness cost [ 62].
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Theory showed that signal costs can ensure truthful communication in such situations, but further studies have cast in doubt whether empirically measured costs are high enough to sustain honesty, and whether the costly signaling equilibrium represents a fitness advantage over non-signaling.
Cold-adapted lines tolerated hot temperatures less than their ancestor, representing a fitness cost of adaptation (Mongold et al. 1996).
To see how sensitive the results are to variations in the fitness function, we consider a different fitness function representing a fitness penalty for aggregation, which we model using a quadratic function of the amount of unfolded protein (4) where is chosen so that at is roughly similar to that in the original model represented by equation (2).
Each module can now be seen as representing a fitness-enhancing (i.e. biologically useful) response to a specific environment.
Wheels incur mechanical and other disadvantages in certain environments and situations, which would represent a decreased fitness when compared with limbed locomotion.
Shorter maturation time and smaller maturation size combined with a faster growth rate could represent a significant fitness benefit for the invasive type.
Notably, Cas9 does not appear to represent a noticeable fitness burden when expressed at a moderate level in fruit flies with or without guide RNAs (Kondo and Ueda, 2013).
If these underlying trends are also expressed in the field, these trends suggest that: (1) early-bolting plants that opt to defer reproduction may die with significant unspent reproductive potential, representing a substantial fitness cost; and (2) late-bolting plants compensate for time-constraints by producing flowers more quickly as the season progresses.
The benefit of each strategy can be represented in a fitness matrix (Fig. 1).
That would represent a risky plan with a fitness cloud over six of the World Cup squad, including Tim Bresnan who is not expected to have recovered from a calf complaint in time for the opening match against Holland on February 22.
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