Sentence examples for represent a defect from inspiring English sources

For the internal validity of this experiment, it is often difficult to represent a defect at a high abstract level since a code defect may refer to detailed contents.

A similar phenomenon was recognized in tumor cells more than 80 years ago [6], and was originally thought to represent a defect in mitochondrial function, perhaps as a result of mutations that occurred during oncogenic transformation.

Alternatively, the accumulation of FA cells in late S/G2 could also represent a defect in recovering from the ATR/CHK1 checkpoint in response to ICL-inducing agents.

These deficiencies, provide further evidence for the role of AGPs in cell wall deposition and growth, and potentially represent a defect in receiving, or responding to, germination cues.

Whether this observation represents a defect in a small subset of arrays, an issue with sub-ideal hybridization conditions, or a general trend in similar arrays, cannot be assessed without further analysis.

Similarly, increased APP immunoreactivity within axons represents a defect in axonal transport and serves as a marker of axonal injury resulting from cytoskeletal breakdown and calcium influx that interrupts axoplasmic flow and subsequent accumulation of organelles [36].

Thus, it seems likely that the reduced capacity of South Asians to oxidise fat during exercise represents a defect in substrate delivery to muscle, rather than in mitochondrial capacity to oxidise lipids.

This uncontrolled immune response likely represents a defect in one or more immunosuppressive mechanisms intended to provide tolerance to the host intestinal microbiota, resulting in the over-production of pro-inflammatory mediators [12], [16] The concept of a balanced immunosuppressive response aimed at regulating the microbiota may be best illustrated in interleukin-10 knock-out (Il10−/−) mice.

It was proposed that cblF represents a defect in the export of cobalamin out of the lysosome into the cytosol (Ref. 82).

Perhaps the more punctuated Don Juan staining pattern in the prenyl protease triple knockout represents a defect along the length of the axoneme membrane, due to improper mitochondrial elongation or to defects in cytoplasmic remodeling.

A subgroup of hypercortisolemic patients with depression, if stimulated with CRH, show a blunted ACTH response, whereas CRH infusion to healthy subjects reproduces the hypercortisolism of depression, suggesting that hypercortisolism in depression represents a defect at the CRHR level, resulting in CRH hypersecretion.