The global diversity of HIV-1 represents a critical challenge facing HIV-1 vaccine development.
The efficient transmission of intense laser light through a plasma while minimizing instabilities represents a critical challenge to the development of laser fusion.
These publications represented a critical challenge to the Argentine literary establishment, which was hitherto almost exclusively comprised of intellectuals belonging to the nation's elite.
Engineering for Sustainable Wastewater Recycling: The shortage of clean water represents a critical challenge for the next century, and has necessitated the recycling of wastewater.
The integration of structural and functional networks represents a critical challenge in connectivity research.
Coercive treatment in its various forms represents a critical challenge for clinical care.
Not only is this a tragic humanitarian disaster for children now, it also represents a critical challenge to peace and stability in Somalia in the future.
Large-scale adoption of recommended protective behaviour represents a critical challenge that cannot be addressed without a better understanding of how individuals perceive and react to the risk of infection.
Identification of modifiable risk factors in midlife, prior to the development of cognitive impairment in old age, represents a critical challenge to improving quality of life and controlling health care costs.
Subgroup-specific modeling of HGA and DIPG associated with these particular alterations presents a challenge and will undoubtedly represent a critical step forward in the study of this multifaceted group of diseases.
