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When comparing groups in this material it must therefore be kept in mind that the non-affected individuals do not represent a background population of healthy dogs but rather dogs with a very similar clinical presentation as the affected.
This does not represent a background staining but a binding with DNA fragments produced by endogenous cytoplasmic endonuclease that is physiologically present, or by antigen retrieval pretreatment [ 10- 122 23, 23].
We find this possibility unlikely especially since the Sox2+, Tbx6+ and TGFP+ expression domains shown in Fig. 2 were in most cases mutually exclusive from each other and very few or no double or triple positive cells (which could potentially represent a background artefact) were observed.
It has been speculated that abnormal pulmonary function tests and asymptomatic high-resolution computed tomography (HRCT) abnormalities seen in JDM may represent a background of subclinical ILD that responds well to conventional immunosuppressive treatment, and therefore needs no further action [ 29].
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We believe that the HPV in this case represents a background "passenger" infection.
The upper black curve is a 30-min scan at 3.785 GBq, the lower black curve is a 30-min scan at 0.613 GBq, the red line represents a background measurement with no source, and the broken red line represents a second-order polynomial fit to the background.
The asterisk represents a background band or degradation product.
This remainder represents a background of noise against which a signal – enrichment of specific sequences – might be detected.
However, these findings do not confirm that the mediastinum represents a background region with only nonspecific uptake/binding.
However, it remains possible that the requirement for PKC merely represents a background PKC activity permissive for the induction of PTP (see discussion in Korogod et al., 2007).
By contrast, when the scan position has been translated into the "sample" region, the visibility A represents a "background term" which consists of the reflection from the coverslip-buffer interface (and the weaker reflection from the optical elements) and B represents the "signal term" that arises from light that is reflected from the sample.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com