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The domain analysis entails curricular (training regulations for schools and for the workplace), instructional (school-books, N = 6), classroom observations with follow-up target group surveys, as well as teacher and trainer interviews and assessment analyses (final exam reports held by the Chamber of Commerce, N = 205).
The ER and PR status were obtained from immunohistochemical testing of tumour tissues or from histopathology reports held by cancer registries (Armes et al, 1999) or diagnostic laboratories (McCredie et al, 2003).
Estrogen receptor (ER) and progesterone receptor (PR) status was obtained either from immunohistochemical testing of tumour tissue [ 20] or from histopathology reports held by the cancer registry or a diagnostic laboratory [ 21].
We found good agreement between the ER and PR status of the tumours recorded on histopathology reports held by the VCR and those obtained from immunohistochemical anlaysis of archival tissue using a standardised protocol.
Similar results were obtained when the analyses were restricted to women born in Australia/New Zealand/the United Kingdom or when excluding the first 2 years of follow-up, or when censoring after 10 years of follow-up or when the analyses by tumour ER and PR status used the data from our own immunohistochemistry only or the data from histopathology reports held by the VCR only (not shown).
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General inclusion criteria for the BRCAX subgroup were families with breast cancer meeting kConFab category 1 and 1B eligibility criteria and with a breast cancer pathology report held by kConFab.
The determinants of reporting main category contained within it a hierarchical structure of categories (primary, secondary and tertiary determinants) that relate to the circumstances and outcomes of the fall, the attitude to reporting held by the staff member, and how busy the staff member is at the time of the fall.
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