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There are several reports for functional complementation of Ubc9 mutant phenotype by expression of DmUbc9 from D. melanogaster[ 38], NbUbc9 from N. benthamiana[ 39], HsUbc9 from H. sapiens[ 40], and OsSce1 from O. sativa[ 22].
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Recently, SB transposon-based mouse models have been reported for functional cancer gene discovery [47], [48].
In our search we also included motifs originally described in other plant species as cross-conservation has been reported for functional cis-elements [ 33].
A trend towards significance was reported for functional well-being, with improved social/family and spiritual well-being scores indicated post-season.
Although true quality of life cannot be measured directly, instruments in the form of questionnaires have been developed that use self-reporting to account for functional performance, health status, and health-related quality of life.
Six studies reported results for functional activity measures [ 16- 19, 21, 23].
Comparison of our functional outcomes with those in Western settings is challenging due to lack of a standardized reporting conventions for functional improvement.
It was previously reported that, for functional expression of certain NIP isoforms in yeast, it is necessary to truncate parts of their hydrophilic N-terminal domain [ 27].
The number of reports using siRNAs for functional genomics applications, for validation of targets for small-molecule drug development programs, and to address questions of basic biology will rapidly grow as methods and protocols for use in animals become more established.
Sample size determination was carried out on the basis of the mean values and standard deviations that have been reported for the functional scores (WOMAC score) associated with septic and aseptic revision of total knee arthroplasty [24].
Some interesting observations were recently reported for developmentally functional A-type lamins in a comparative study of Drosophila and humans [25] [67].
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