Where ventilator-free days were reported, ventilation time was derived using the period over which ventilator-free time was measured.
Additionally, household income below $20,000, which had the least amount of missing data, was included in each model because prior research has demonstrated a strong association between income and reported ventilation use.
Pooled data from 14 trials reporting total ventilation duration indicated a reduction favouring automated systems (mean log hours −0.11, −0.18 to −0.03, P = 0.005; 10%3%3% to 16%) reduction in geometric mean) with no heterogeneity (I = 0%, P = 0.62).
One small study (Knibbs et al. 2008) reported low ventilation rates in vehicles with ventilation systems in the closed or recirculated-air positions.
Although after stratifying by sex, we observed that the percent-predicted FEV1 was almost 3% higher in girls (p = 0.02) that lived in homes where parents reported using ventilation compared to homes where ventilation was not used.
The crude prevalence of parental-reported pneumonia was higher among children where the respondents did not report using ventilation compared to those who reported using ventilation (4.17% [95% CI: 2.71, 5.63] versus 2.41%[955% CI: 1.64, 3.18], p < 0.05).
The adjusted odds of asthma (Odds Ratio [OR] = 0.64; 95% confidence intervals [CI]: 0.43, 0.97), wheeze (OR = 0.60, 95% CI: 0.42, 0.86), and bronchitis (OR = 0.60, 95% CI: 0.37, 0.95) were lower among children whose parents reported using ventilation compared to children whose parents reported not using ventilation when operating gas stoves.
The odds of pneumonia (aOR = 1.76, 95% CI: 1.04, 2.98), but not cough (aOR = 1.23, 95% CI: 0.87, 1.75), was higher among those children whose parents did not report using ventilation when operating gas stoves compared to those who did use ventilation.
Overall, the unadjusted prevalence of wheeze (14.2% vs. 19.3%, p-value = 0.01, N = 7,380) and bronchitis (3.2% vs. 5.0%, p-value = 0.02, N = 7,378) were lower among children residing in households that reported using ventilation when operating their gas stoves compared to households that did not use ventilation when operating their gas stove.
This study reports the ventilation and oxygenation delivered by IntelliVent-ASV® in long-term ventilated ICU patients.
