Caregiver-report of last missed ART dose had a relatively high agreement with MEMS.
We determined gestational age from mother's report of last menstrual period and medical record report of infant's date of birth.
Estimated date of conception (EDC) assessed using maternal report of last menstrual period (LMP) combined with ultrasound at ≤20 weeks gestation was used to determine PTD.
Gestational age was defined in the SMBR according to maternal report of last menstrual period and clinical judgement by the attending paediatrician.
Gestational age is determined by maternal report of last menstrual period at study enrollment using prospectively completed study calendars, and in a subset by early (<20 week) ultrasound.
Our calculated mean and median lengths for all human last exons, 1,398 and 1,003, respectively are considerably longer than previous reports of last exon length [ 26- 28], the longest mean of which was 811 bp.
The exposure of interest was gestational age at birth, which was based on maternal report of last menstrual period and categorized as 23 28, 29 34, 35 36, 37 42 (full term), and ≥43 weeks.
Another limitation is the estimation of gestational age by maternal report of last menstrual period rather than by ultrasound, which was not yet widely used at the time these study participants were born (1973 1979).
Gestational week at delivery was calculated from the estimated gestational week at enrollment, which was based on clinical examination (fundal height) and self-report of last menstrual period (LMP).
